Recent Advances on the Synthesis, Reactions and Evaluation of the Pharmacological Properties of Quinoxaline, Quinoxaline-2-One and Quinoxaline-2,3-Dione
Festus O. Taiwo *
Department of Chemistry, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria.
David A. Akinpelu
Department of Microbiology, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria.
Craig A. Obafemi
Department of Chemistry, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
The review article attempts to give recent advances on quinoxaline and its derivatives. Some pathways to the synthesis of quinoxaline, quinoxaline-2-one and quinoxaline-2,3-dione were reported using simple reactive quinoxaline synthon. In addition, the reactions, biological and technological applications of derivatives of quinoxaline and related compounds were reported.
Keywords: Quinoxaline, Quinoxaline-2-one, Quinoxaline-2,3-dione, Pharmacological properties