Chemistry and Biological Importance of Heterocyclic Schiff’s Bases
Mithun Rudrapal *
Aditya Institute of Pharmaceutical Sciences and Research, Surampalem, E. G. District, Andhra Pradesh, India
Biplab De
Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala, Tripura, India
*Author to whom correspondence should be addressed.
Abstract
Schiff’s bases containing heterocyclic scaffolds have been known to possess a wide range of biological and pharmacological activities for a long time. In recent years, they have gained significant interest in the area of drug research and development owing to their broad bioactivities such as antibacterial, antifungal, anti-inflammatory, anticonvulsant, antiviral and anticancer activities. In this paper, biologically relevant Schiff’s bases derived from a diverse group of heterocyclic scaffolds have been intensively reviewed.
Keywords: Heterocyclic, Schiff’s base, biological activity, lead molecule